Some new studies have found an increased risk of heart attack in testosterone treatment of men with testosterone deficiency.
Some new studies have found an increased risk of heart attack in testosterone treatment of men with testosterone deficiency, but the results are spreading and several studies have methodological weaknesses that make it difficult to draw safe conclusions. In addition, the lack of testosterone in itself may increase the risk.
Also read: Testosterone and heart disease and Testosterone therapy
European Medicines Agency has assessed the studies and concluded that it is not unambiguously proven that such treatment increases the risk of cardiovascular events.
Also read: Symptoms of low testosterone in men
Advice for doctors:
– Substitution treatment with testosterone is indicated only when testosterone deficiency has been confirmed both in clinical symptoms and laboratory studies. Monitor testosterone levels, hemoglobin, hematocrit, liver function and lipid profile
– For treatment in patients with high blood pressure, blood pressure must be monitored carefully
– The treatment may cause edema in patients with impaired cardiac, hepatic or renal function and in patients with coronary heart disease
– There is limited experience with such treatment in men over 65 years of age